ERp46 |
ER-phagy |
Glucocorticoid-induced gene 18 protein |
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[ER protein 99] This protein is an abundant, conserved transmembrane glycoprotein of the endoplasmic reticulum. Its expression is upregulated in resting B-cells induced to differentiate antibody-secreting cells in response to bacterial lipopolysaccharides (Lewis et al, 1985). The cDNA has been isolated by Mazzarella and Green (1987). The protein shows extensive homology with heat shock proteins from yeast and Drosophila melanogaster and appears to be a variant of heat shock protein GP96.
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