EPLG8 |
EPLIN-alpha |
Lymphocyte antigen 71 |
||
[Epithelial Protein Lost In Neoplasm] The approved gene symbol is LIMA1 [LIM domain and actin-binding protein 1]. The cDNA sequence has been deposited in sequence databanks as SREBP3 [Sterol regulatory element-binding protein 3].
This cytoskeletal protein is expressed preferentially in human epithelial cells. Maul and Chang (1999) have described two different isoforms, EPLIN-alpha (600 amino acids) and EPLIN-beta (759 amino acids), which are transcribed from two different promoters (Chen et al, 2000). Both proteins contain a centrally located LIM domain. Both proteins are expressed in primary
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