EMMPRIN

[extracellular matrix metalloproteinase inducer] This glycoprotein factor of 58 kDa was originally termed tumor cell-derived collagenase stimulatory factor (TCSF). It was found to be elaborated by the human lung carcinoma cell line LX-1. The protein is expressed also by normal human keratinocytes.

Computer database searches of cDNA sequences indicate that EMMPRIN is a member of the immunoglobulin superfamily (see also: gene family) and that the deduced amino acid sequence of EMMPRIN is identical with that reported for human Basigin and M6 ... ... ... ...
 
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Entry last modified: July 2003