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EMMPRIN

[extracellular matrix metalloproteinase inducer] This glycoprotein factor of 58 kDa was originally termed tumor cell-derived collagenase stimulatory factor (TCSF). It was found to be elaborated by the human lung carcinoma cell line LX-1. The protein is expressed also by normal human keratinocytes.

Computer database searches of cDNA sequences indicate that EMMPRIN is a member of the immunoglobulin superfamily (see also: gene family) and that the deduced amino acid sequence of EMMPRIN is identical with that reported for human Basigin and M6 antigen, molecules of previously undetermined biological function. EMMPRIN and ... ... ... ... ... Subscribe to continue reading! ... ...

 

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