EMAP-2

[Endothelial-monocyte activating polypeptide-2] This factor (approximately 22 kDa) is secreted into the conditioned medium of murine methylcholanthrene induced meth A fibrosarcoma cells (Kao et al, 1992, 1994) together with another unrelated factor, EMAP-1.

The human cDNA encodes a protein of 312 amino acids. Human and mouse EMAP-2 amino acid sequences share 86 % identity (Kao et al, 1994). EMAP-2 is being referred to also as SCYE1 [small inducible cytokine subfamily E member 1] (see also: SCY family of cytokines). The approved gene symbol for this protein is AIMP1 [ ... ... ... ...
 
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Entry last modified: January 2006