AIM2 inflammasome |
AIMP1/p43 |
Cystatin M |
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[ARS-interacting multi-functional protein 1; aminoacyl tRNA synthetase complex interacting multifunctional protein 1] This protein has been identified as an auxiliary factor bound to the multi-ARS (aminoacyl-tRNA synthetase) complex (Deutscher et al, 1974; Dang and Yang, 1982; Mirande et al, 1982; Yang et al, 1985). AIMP1 has been shown to interact with arginyl-tRNA synthetase and to enhance its enzymatic activity (Park et al, 1999).
The protein is known also as EMAP-2 (Endothelial-monocyte activating polypeptide-2] or SCYE1 [small inducible cytokine subfamily E member 1]. Sequence analysis shows that the protein is identical with p43 (hence also the composite term AIMP1/p43
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