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ELAM-1

[endothelium leukocyte adhesion molecule 1] ELAM-1 (also: ELAM) is a cell surface glycoprotein expressed by cytokine-activated endothelium and mediates the adhesion of blood neutrophils. The expression of ELAM-1 in cultured human endothelial cells is induced by cytokines.

The gene encoding this protein has been cloned by Bevilacqua et al (1989). It is related to the MEL-14 lymphocyte cell surface homing receptor, and GMP-140, a membrane glycoprotein of platelet and endothelial secretory granules. In the nomenclature of CD antigens the new designation of this protein is ... ... ... ... ... Subscribe to continue reading! ... ...

 

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