Comet assay |
command neuron peptide 1 |
Herpes simplex virus alpha22 protein |
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Cometin is a secreted neurotrophic factor that, together with Meteorin, defines a new evolutionary conserved protein family of neurotrophic factors (Jørgensen et al, 2012). During early mouse development, Cometin is found exclusively in the floor plate and from E13.5 also in dorsal root ganglions and inner ear but apparently not in the adult nervous system. In vitro, Cometin promotes neurite outgrowth from dorsal root ganglion cells. Cometin supports the migration of neuroblasts from subventricular zone explants to the same extend as SDF-1-alpha. Cometin also supports survival and function of spiral ganglion neurons in vivo.
The approved gene symbol is
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