CL100

CL100 has been identified as an early response gene the transcription of which is stimulated rapidly and transiently up to 40-fold in human skin fibroblasts exposed to oxidative/heat stress and growth factors (Keyse and Emslie, 1992). The protein has been identified independently as AURA23 [augmented in rheumatoid arthritis 23].

The human gene has been termed DUSP1 [dual-specificity phosphatase 1] and an older designation is PTPN10 [protein-tyrosine phosphatase nonreceptor-type 10]. Sequences among species are highly conserved. Human, rodent, and ... ... ... ...
 
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Entry last modified: March 2004