Cementum mitogenic factor |
Ce-MIF |
Hsp27(93-113) |
||
[Corneal endothelium modulation factor] This biochemically uncharacterized factor is secreted by polymorphonuclear leukocytes. It affects a population of rabbit corneal endothelial cells with polygonal cell shape by modulating them to fibroblast-like cells and by further stimulating their growth, leading to the formation of colonies of multilayered nodulated cells (see also: Colony formation assay).
CEMF also induces the synthesis of collagen type 1 (fibrillar collagen) and leads to a dramatically reduced amount of collagen type 4 (basement membrane collagen) in the endothelial cells.
CEMF significantly increases the production of bFGF in corneal
...
...
...
...
... Subscribe to continue reading!
... ...
Content view restricted ! |