CD247 |
CD249 |
lymphocyte chemokinetic activity |
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[CD248(+), CD248(-)]
Other designations:
TEM1 [Tumor endothelial marker 1]
This protein is expressed predominantly and at elevated levels on the cell surface of endothelial cells in newly developing blood vessels and on tumor cells (see: TEM1). MacFadyen et al (2005) have reported that endosialin is a marker of stromal fibroblasts and pericytes and is not selectively expressed on tumor endothelium. Expression of CD248 has been reported also on vascular leukocytes, a subset of leukocytes expressing markers of dendritic cells
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