BAM-1745 |
BAM domain |
VLCIENSFMTASK |
||
(approved gene symbol) [BMP and activin membrane-bound inhibitor] The protein has been identified independently as NMA [Non-metastatic gene A protein].
BAMBI is a transmembrane protein identified by Onichtchouk et al (1999). BAMBI is a non-signaling, competitive pseudoreceptor related to TGF-beta family type 1 receptors that lacks an intracellular kinase domain. BAMBI has been shown to interfere with signaling of bone morphogenetic proteins and Activin A by inhibiting TGF-beta receptor type 1 activation. In contrast to other BMP antagonists like noggin or chordin, BAMBI is strictly coexpressed with BMP4 during early Xenopus laevis
...
...
...
...
... Subscribe to continue reading!
... ...
Content view restricted ! |