AMH receptor |
Amida |
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[AIF-homologous mitochondrion-associated inducer of death] AMID shares significant homology with AIF and NADH oxidoreductases from bacteria to mammalian species. The gene is known also as PRG3 [p53-responsive gene 3]. The approved gene symbol is AIFM2 [apoptosis inducing factor mitochondrion associated 2; mitochondrion associated apoptosis inducing factor-2].
AMID is localized preferentially in the outer mitochondrial membrane or the cytoplasm (Ohiro et al, 2002; Varecha et al, 2007; Wu et al, 2002). Yang et al (2011) have shown that adenosine increases the expression of AMID in HuH-7 hepatoma cells, and stimulates its translocation from the cytosol into the nucleus.
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