AMF/PHI |
AMG 114 |
RPPGFSPFR |
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[autocrine motility factor receptor] The cDNAs encoding the mouse and human receptor for AMF [autocrine motility factor], an extracellular cytokine that is identical with the glycolytic enzyme phosphoglucose isomerase (PGI), have been cloned by Shimizu et al (1999). Both deduced proteins contain 643 amino acids and share 94.7 % amino acid identity. Watanabe et al (1991) have cloned the gene encoding the receptor, which is the same as gp78 [glycoprotein 78]. AMFR can be detected specifically by monoclonal antibody 3F3A (Nabi et al, 1990; Registre M et al, 2004). Given the identity of the autocrine motility factor /
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