AMBRA1

[Activating molecule in BECN1-regulated autophagy protein 1, activating molecule in Beclin1-regulated autophagy 1; autophagy/beclin-1 regulator 1] This protein has been identified independently as KIAA1736 and DCAF3 [Ddb1- and Cul4-associated factor 3]. A databank synonym is WDR94 [WD repeat domain 94].

Mouse AMBRA1 encodes a deduced 1,300 amino acid protein with an N-terminal WD40 domain. Human AMBRA1 encodes a deduced 1,269 amino acid protein (Fimia et al, 2007). Fimia et al (2007), who coined the term AMBRA1, have shown that human AMBRA1 binds to ... ... ... ...
 
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Entry last modified: September 2023