AI amacrine cells |
AIC2B |
growth hormone inducible gene-3 |
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[AIC = activation induced] This murine protein is identical with the IL3-binding beta subunit of the murine receptor for IL3. The murine protein designated AIC2B is a homologous but separate gene, displaying 91 % sequence identity at the amino acid level with AIC2A, and does not bind IL3.
AIC2B is a subunit required for the generation of high-affinity receptors for IL5 and GM-CSF. AIC2B and AIC2A are homologous with the beta c (betac, common beta) subunit of the human cytokine receptors for
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