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AE1

[anion exchanger 1; anion exchange protein 1] AE1 is a member of a protein family of anion exchangers that mediate the exchange of anions across the plasma membrane. AE1 and some other members of this family (AE2 and AE3) are related to erythrocyte band 3 protein (Kopito, 1990; Alper, 1991). The AE1 gene, which encodes the band 3 protein, is expressed coordinately with other erythroid genes during erythropoiesis in both avian and mammalian erythroid progenitor cells (Tanner, 1993). It is expressed also at the basolateral plasma membrane of the acid-secreting intercalated cells of the kidney. The analysis of major AE1 transcripts in ... ... ... ... ... Subscribe to continue reading! ... ...

 

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