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intercalated cells

[intercalated cell, intercalated cells of the kidney]

Renal intercalated cells (also kidney intercalated cells or collecting duct intercalated cells) are a distinct type of epithelial cells in the collecting tubules of the kidney (Schwartz et al, 1985; Al-Awquati and Gao, 2011). These cells mediate acid-base transport and are responsible for acidification and alkalinization of urine. In some older publications intercalating cells are being referred to as dark cells, a term reflecting their staining behaviour in histological stains (Wettstein and Tiedemann, 1981; Nicholson and Kendall, 1983; Evan et al, 1991; Nouwen and De Broe, 1994).

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