ADAMTS11 |
ADAMTS13 |
integrins |
||
[a disintegrin and metalloproteinase with thrombospondin motif-12; ADAM metallopeptidase with thrombospondin type 1 motif 12] This protein is a member of the ADAMTS protein family. This protein is a member of the ADAMTS protein family. The cDNA for this protease has been isolated from a fetal lung cDNA library following a search in an EST database for sequences similar to other members of the ADAM protein family (Cal et al, 2001). The ADAMTS12 gene maps to human chromosome 5q35.
The secreted protein (1,543 amino acids) is 57 % identical with ADAMTS7 and contains 8 uniquely organized thrombospondin repeats
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