adamtsostatin-like-4 |
ADAMTSR1 |
YPWFamide |
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[ADAMTS family]
ADAMTS proteins are structurally related to ADAM protein family in that they contain a disintegrin and a metalloprotease domain. A collective term for members of this protein family is metallospondins. ADAMTS proteins lack the EGF-like domain found normally in members of the ADAM protein family. They also do not possess the canonical disintegrin sequence found in the ADAM protein family (Tang and Hong, 1999; Porter et al, 2005; Apte, 2009).
In addition, ADAMTS proteins also contain varying numbers of a thrombospondin type 1 motif. ADAMTS proteins contain a signal sequence and are secreted rather than membrane bound proteins.
Members of this family include
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