1C7

The gene encoding this protein has been identified by Nalabolu et al (1996) as a homolog of murine B144 located in a 220 kb region around the TNF gene cluster in the human central major histocompatibility complex region. It is expressed in spleen and thymus, and prominently in the macrophage cell line U937. The sequence is identical with NKp30.

Several different splice variants yielding proteins with unique carboxy termini have been observed in humans. 1C7 protein is expressed in NKL cells, a cell line resembling activated NK-cells, tonsil, and in brain (Sivakamasundari et al, 2000). The 1C7 gene of the ... ... ... ...
 
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