schistocytes

This term refers to red blood cells thaqt are damaged as a result of erythrocyte fragmentation (Lesesve et al, 2005). Typically, schistocytes are irregularly shaped, jagged, and have two pointed ends.

The presence of such fragmented cells is due to mechanical injury and thus is an important diagnostic marker for thrombotic microangiopathies (Klein et al, 1975; Ward, 1979.

Bunyaratvej et al (1985) have reported reduced numbers of normally shaped erythrocytes (see: discocytes) in patients with beta-thalassemia/HbE disease, which is reduced further by splenectomy, larger splenic sizes, and increasing anemia. The numbers of dacryocytes, keratocytes ... ... ... ...
 
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Entry last modified: October 2006