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sFRP2

[secreted frizzled-related protein 2] A databank synonym for this protein is FKSG12.

This protein, which is being referred to also as FRP2 [frizzled-related protein 2], is a member of a family of secreted proteins that appear to act as soluble modulators of Wnt family signaling. They compete with membrane-bound receptors belonging to the frizzled family for the binding of secreted Wnt family ligands (Jones and Jomary, 2002). The mouse gene has been identified originally by Rattner et al (1997) as a member of a family of mammalian genes that encode secreted proteins ... ... ... ... ... Subscribe to continue reading! ... ...

 

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