placensin

this secreted protein, which shows high expression in trophoblasts of human placenta (Yu Y et al, 2020), has been identified as a peptide hormone encoded by FBN2 [fibrillin-2], a structural component of 10-12 nm extracellular calcium-binding microfibrils. Placensin corresponds to FBN2(2780-2912) [Fibrillin-2(2780-2912)]. The hormone is generated by furin cleavage of the C-terminal region of profibrillin-2, similarly to asprosin cleaved from the fibrillin-1 precursor. For a collective term for factors generated from the C-terminal end of larger precursor parent proteins see also: Caudamins.

Placensin stimulates cyclic ... ... ... ...
 
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Entry last modified: January 2024