laminin-alpha-1(2099-2104) |
Laminin-alpha-1(2747-2765) |
H89 |
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[LAMA1(2719-2730); LN-1(2719-2730); LMN-1(2719-2730)] (Malinda et al, 1999). This bioactive fragment of laminin-alpha-1, termed AG73 peptide (RKRLQVQLSIRT) has been identified by Nomizu et al (1995) by virtue of its cell binding activity to various tumor cell lines (HT-1080 human fibrosarcoma, B16-F10 mouse melanoma and SW480 human colon adenocarcinoma cells). The minimum sequence required for cell adhesion is LQVQLSIR. The peptide enhances in vitro adhesion, migration, invasion and gelatinase
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