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[Gram-positive Specific Serine protease] The Drosophila melanogaster serine protease Grass, encoded by gene CG5896, has been identified by Kambris et al (2006) in a screen for proteases required for the activation of the Toll receptor, which plays a key role in embryo patterning and immune responses.

El Chamy et al (2008) have demonstrated that Grass defines a common activation cascade for the detection of fungi and Gram-positive bacteria. Grass functions downstream of pattern recognition receptors and upstream of Spätzle processing enzyme, the enzyme that activates protein Spätzle into a ligand form that can bind to the ... ... ... ... ... Subscribe to continue reading! ... ...

 

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