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fra-1

[fos-related antigen 1] This antigen is known also as FOSL1 [FOS-like antigen 1], which is the approved gene symbol.

Fra-1 is an early response gene the transcription of which is rapidly and transiently stimulated in diverse cell types following mitogenic stimulation of cells with serum (Cohen and Curran, 1988). The protein shows several regions of extensive amino acid homology with fos. Only a subset of the agents and conditions that activate fos expression also induce fra-1 expression. fra-1 has been shown to be one of the subunits of NF-AT (nuclear factor for activated T-cells), a transcriptional complex which mediates the expression of ... ... ... ... ... Subscribe to continue reading! ... ...

 

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