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diffuse neuroendocrine system

[diffuse neuroimmunoendocrine system, neuroendocrine system]

abbr. DNES. A collective term for a set of (unrelated) neuronal and endocrine cells (see, e. g., APUD cells). The term has been extended by the inclusion of immunocompetent cells (neuroimmunoendocrine system; abbr. DNIES).

These cells secrete a variety of products, including low molecular weight substances, cytokines, chemokines. These substances act via neurocrine, endocrine, and paracrine mechanisms and maintain homeostasis by allowing communication and reciprocal regulation between the nervous, endocrine, and immune systems (Polak and Bloom, 1986; Salzet, 2002; Sternberg et al, 2000; Weigent and Blalock, 1997; Rivest, 2010). Together these cells ... ... ... ... ... Subscribe to continue reading! ... ...


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