complement S protein |
Complex III subunit 3 |
Brichos domain containing 1 |
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This bioactive peptide fragment (see also: cryptides) is derived from C6 [Complement component C6] (Karagiannis and Popel, 2007). Complestatin-C6 [C6(30-48); Complement component C6(30-48)] [TQWTSCSKTCNSGTQSRHR] corresponds to residues 30-48 of Complement component C6 (Karagiannis and Popel, 2008). The primary structure of this peptide is similar to the thrombospondin type 1 domains found in thrombospondin-1, thrombospondin-2, the metalloproteinases ADAMTS1 and ADAMTS8. The peptide functions as an inhibitor of angiogenesis
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