bFGF(48-58) |
BFGFR |
HCRTR1 |
||
[bFGF/uPA inducing activity; urokinase plasminogen activator inducing activity] This biochemically uncharacterized factor of approximately 18 kDa is found in conditioned medium by human SK-Hep1 hepatoma cells or mouse S180 sarcoma cells. The activity rapidly upregulates endothelial cell expression of bFGF and induces the formation of capillary-like structures by vascular endothelial cells grown on three-dimensional fibrin gels (in vitro angiogenesis).
The activity also induces endothelial cells to increase expression of urokinase plasminogen activator (uPA), a key
...
...
...
...
... Subscribe to continue reading!
... ...
Content view restricted ! |