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YT

An EBV-positive human natural killer-like leukemic cell line established from a patient with acute lymphoblastic lymphoma and thymoma. The cells have been used to study expression of IL2 receptors and to investigate natural killer cell biochemistry.

YT-cells are independent of IL2 and proliferate continuously in vitro without conditioned medium. The cells proliferate in response to IL1. YT-cells constitutively expressed IL10 mRNA and protein.

YT-cells are cytolytic for a variety of human cell lines and displays spontaneous cytotoxicity against CD80(+) and/or ... ... ... ...
 
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Entry last modified: March 2010



 
 
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