YAC-1

A murine T-lymphoma cell line sensitive to NK-cells, established from a tumor induced by Moloney sarcoma virus in A/Sn mice. The cells do not express Fc receptors. Among other things these cells are used to study the cytotoxic activities of naturally occurring killer cells, LAK cells (lymphokine-activated killer cells), and factors influencing the cytotoxic activities of these and other lymphocytes. YAC-1 cells are lysed by NK-lysin.

For an overview of other cell lines used in research on cytokines see: Cell lines in Cytokine Research ... ... ... ...
 
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Entry last modified: July 1998