Wnt-4 |
Wnt-5a(317-322) |
ISG20L1 |
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[Wnt family member 5a; wingless-type MMTV integration site family member 5a] Wnt-5a is one member of the so-called Wnt family of proteins (Nusse et al, 1991), identified by Gavin et al (1990) by virtue of sequence homology to Wnt-1. Clark et al (1993) have cloned the human gene shown shown that Wnt-5a is expressed only in neonatal heart and lung. Human Wnt-5a shows over 99 % amino acid sequence homology with mouse Wnt-5a, and 90 % with Xenopus laevis Wnt-5a (Lejeune et al, 1995). For a bioactive peptide derived from Wnt-5a (Wnt-5a(317-322)) see: Foxy5.
He et al (1997) have shown that human
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