Wegener Autoantigen |
WEHD-AFC |
proliferin-related protein |
||
The tetrapeptide sequence WEHD (Trp-Glu-His-Asp) has been found to be the optimal tetrapeptide recognition sequence for one of the caspases, IL1-beta Convertase (Rano et al, 1997). Some other caspases (caspase-4, caspase-5) also prefer this tetrapeptide sequence (Garcia-Calvo et al, 1998; Rano et al, 1997). Hibino et al (2010) have reported that purified active caspase-14 from human cornified cells has the highest activity on WEHD-AFC (conjugated to 7-amino-4-trifluoromethylcoumarin). An enzyme that recognizes the WEHD sequence is referred to sometimes also as WEHDase and would thus be caspase-1, caspase-4,
...
...
...
...
... Subscribe to continue reading!
... ...
Content view restricted ! |
| SUPPORT COPE | Intro | Subdictionaries | New Entries | Contribute data | COPE Credentials |
| # | A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z |
|
Created, developed, and maintained by Dr H Ibelgaufts
|
U L T R A P O S S E N E M O O B L I G A T U R