WC6

[workshop cluster 6] Gliddon et al (2004) have shown WC6 to be the bovine ortholog of human CD205.

This antigen has been identified by Parsons et al (1993) as a 210 kDa molecule present on all bovine CD2(+) cells and B-cells. It is not expressed by WC1(+) Gamma-Delta T-cells. The antigen is expressed on dendritic cells (Gliddon et al, 2004; Howard et al, 1996).

In sheep, three WC6 anti-bovine monoclonal antibodies (CC98, IL-A114, IL-A53) stain less than 30 % of lymphocytes from blood, efferent and afferent lymph and the majority of afferent lymph dendritic cells. They also weakly stain ... ... ... ...
 
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