Ventroptin

abbr. VOPT. Chicken ventroptin acts as an antagonist of BMP4. It is expressed mainly in the ventral retina (Sakuta et al, 2001).

The protein contains a putative signal peptide and 3 cysteine-rich repeats similar to those found in other proteins interacting with BMP4 (see: chordin). Ventroptin is likely to be a secreted protein as it is found in the conditioned medium of chick embryonic fibroblasts infected with a recombinant virus expressing ventroptin (Sakuta et al, 2001). Two splice variants of mouse ventroptin have been described. Ventroptin-alpha is the long form. Ventroptin-beta ... ... ... ...
 
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Entry last modified: June 2017