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VEGF-115

[VEGF-A115] [Vascular endothelial growth factor-115] one of the four splice variants of murine VEGF (Sugihara et al, 1998). The corresponding VEGF-115 factor is found in the conditioned medium of spontaneously immortalized mouse fibroblasts (RS-4), an immortalized clone from CD1-ICR mouse embryonic fibroblasts and was identified originally as a growth-supporting activity for human umbilical vein endothelial cells (Kaul et al, 1994; Sugihara et al, 1994).

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