ULK1 |
Ultrabithorax |
shedding vesicles |
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[unc-51-like kinase 2] This protein is a serine/threonine kinase related to ULK1. It is a mammalian counterpart of the Caenorhabditis elegans UNC51 [uncoordinated locomotion-51] gene.
The mouse gene has been cloned by Yan et al (1999). The cDNA has been cloned independently as KIAA0623. The protein is being referred to also as ATG1B [autophagy related-1B] and UNC51.2.
Lee and Tournier (2011) have demonstrated that ULK2 and the related ULK1 are functionally redundant protein kinases required to mediate autophagy
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