U90926

This term pertains to a mouse gene encoding a long non-coding RNA. While U90926 RNA levels are minimal in multiple tissues at steady state, the expression of this gene is highly induced in macrophages and dendritic cells in response to activation of Toll-like receptors. U90926 RNA has been shown to localize to the cytosol, associates with ribosomes, and contains an open reading frame that encodes a glycosylated protein (termed U9-ORF), which is secreted from the cell and may act in a paracrine and/or endocrine manner. In comparison with wild-type mice, U9-ORF knock-out mice ... ... ... ...
 
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Entry last modified: March 2023