Tim-2 |
Tim-3L |
VP neurons |
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[T-cell immunoglobulin and mucin domain-containing protein 3; T-cell membrane protein 3; T-cell immunoglobulin mucin 3; T-cell Ig mucin 3] abbr. also: Timd3. In the nomenclature of CD antigens the protein has been given the designation CD366.
Mouse and human cDNAs have been cloned by Monney et al (2002). Tim-3 is a type 1 membrane protein with an immunoglobulin variable-like domain, a mucin-like domain, and a cytoplasmic domain with a tyrosine phosphorylation motif. A truncated secreted form of Tim-3 lacking the mucin and transmembrane
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