TREML4

[triggering receptor expressed on myeloid cells-like 4; Trem-like protein 4]. An alternative designation is TLT-4 [Trem-like transcript 4 protein].

TREML4 has been identified by Hemmi et al (2009) as a gene that is expressed more prominently in CD8-alpha(+) than CD8-alpha(-) dendritic cells. Expression is seen predominantly in the spleen. High levels are seen on splenic macrophages in the spleen, particularly red pulp and marginal metallophilic macrophages. TREML4 expression on dendritic cells is not changed after maturation induced by TLR ligands. The protein has been shown to be able to bind to late apoptotic or ... ... ... ...
 
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Entry last modified: April 2016