SWIP1 |
Swiss 3T3 cells |
autophagy related 16 like 1 |
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Approved gene symbol: EFHD2 [EF-hand domain containing protein D2] This protein has been identified by Vuadens et al (2004) in a search for proteins that discriminate CD8(+) from CD4(+) and CD19(+) T-cells. Swiprosin-1 is associated preferentially with CD8(+) lymphocytes. Swiprosin-1 contains two potential EF-hand domains, and therefore may have a role in calcium signaling. Its predominant presence in CD8(+) T-cells suggests that it may be involved in functions that are important for cytotoxic lymphocytes.
Mielenz et al (2005) have identified Swiprosin-1 in lipid raft proteins from mature and immature B-cell
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