SRDLICYCRKGGCNRGEQVYGTCSGRLLFCCRRRHRH |
SREB3 |
CMRF35-like molecule-7 |
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[SREs]
[serum response element] A short sequence found in the promoter regions of a number of cytokine genes and genes the expression of which is stimulated by cytokines and growth factors (see, for example: Egr-1) (see also: gene expression). This sequence element mediates the inducible expression of these genes by several external and intracellular signaling molecules including serum (and factors contained therein), 12-O-tetradecanoyl-phorbol-13-acetate (see also: Phorbol esters), cAMP, and membrane-associated tyrosine kinases such as src, fps, raf, and ras.
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