SPY3-2

This spleen stromal cell line with a fibroblastoid morphology was established from a three-dimensional spleen primary culture in collagen gel matrix.

SPY3-2 cells do not express markers of pre-adipocytes and endothelial cells and are not converted to adipocytes in the presence of hydrocortisone. SPY3-2 cells express high levels of SCF and low levels of GM-CSF and IL3.

SPY3-2 cells support the maintenance and differentiation of hematopoietic progenitor cells (see also: hematopoiesis, BMC) into predominantly monocytes. Epo induces ... ... ... ...
 
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Entry last modified: June 1996