SIFamides

SIFamides are a group of highly conserved neuropeptides found in arthropods, nematodes, molluscs, annelids (Verleyen et al, 2004, 2009; Jékely, 2013; Mirabeau and Joly, 2013; Veenstra, 2010, 2011; Christie et al, 2011). In insects, SIFamides are prominent in holometabolous species, i.e., those with a complete metamorphosis, and have not been found in hemimetabolous insects.

In Drosophila melanogaster, SIFamide, termed SIFa, (gene: CG33527) is an amidated dodecapeptide (AYRKPPFNGSIFamide) (Vanden Broeck, 2001; Janssen et al, 1996). The SIFamide precursor gene is expressed in four neurons located in the pars intercerebralis, a neuroendocrine ... ... ... ...
 
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Entry last modified: October 2014