SD-BMSC

[serum deprivation-induced bone marrow stem cells] These cells constitute a subpopulation of pluripotent stem cells in the bone marrow (see also: BMSC). SD-BMSC are induced as a distinct subpopulation after complete serum deprivation. These cells are generated from small-sized bone marrow stem cells that express nestin (referred to as S-BMSC by the authors) and are organized as round-shaped cells in the top layer of bone marrow stem cell cultures. The generation of SD-BMSC is caused by a selective proliferation of S-BMSC and is accompanied by changes in both morphology and gene expression. SD-BMSC upregulate the expression of markers typical for neural stem cells like ... ... ... ...
 
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Entry last modified: January 2009