SCS-alpha |
SCT |
NCA-160 |
||
[Sertoli cell secreted growth factor] This biochemically uncharacterized factor (smaller than 9.5 kDa) is found in conditioned medium from cultures of rat Sertoli cells. Addition of follicle-stimulating hormone, testosterone, retinol, and insulin to the Sertoli cells increases the secretion of the mitogenic activity (Buch et al, 1988; Lamb et al, 1991).
Peritubular cells enhance Sertoli cell attachment and SCSGF secretion. Spermatogenic cells have no effect. The secretion of SCSGF is stimulated specifically by follicle-stimulating hormone (FSH) and testosterone (Shubhada et al, 1993).
The factor is a potent
...
...
...
...
... Subscribe to continue reading!
... ...
Content view restricted ! |