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Royalisin

Royalisin (VTCDLLSFKGQVNDSACAANCLSLGKAGGHCEKVGCICRKTSFKDLWDKRF) has been found in royal jelly of the honeybee Apis mellifera (Fujiwara et al, 1990). Royalisin is a peptide of 51 residues and three intramolecular disulfide linkages. Klaudiny et al (2005) have reported that royalisin is identical with a defensin found in the hemolymph of bacterially infected bees. Both peptides are encoded by the same polymorphic gene, which the authors have termed defensin1 (see also: defensins).

Royalisin shows extensive sequence homology to two other antibacterial proteins, sapecin and phormicins. The peptide possesses potent antibacterial activity against Gram-positive bacteria, but not against ... ... ... ... ... Subscribe to continue reading! ... ...

 

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