Robo-1

[roundabout-1; roundabout homolog 1; roundabout guidance receptor 1] The human robo-1 protein (1,395 amino acids; often referred to as H-Robo-1) is a member of the subfamily of immunoglobulin superfamily proteins that is highly conserved from fruit flies (see: robo) to mammals (Kidd et al, 1998). Human and rat Robo-1 proteins share greater than 95 % sequence identity.

The Caenorhabditis elegans gene sax3 has been identified as a homolog of Robo-1 that also mediates cell interactions during guidance decisions (Zallen et al, 1998).

The gene has been identified independently as ... ... ... ...
 
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Entry last modified: November 2009