resting regulatory T-cells |
resting cells |
augmented expression in SLE 2 |
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This is a 22 kDa fragment derived from the NC10 domain of human collagen type 15. It is a close homolog of Endostatin (Ramchandran et al, 1999; John et al, 1999) (not to be confused with Restin (Reed-Sternberg microtubule-associated protein, CLIP170), a cytoplasmic linker protein mediating the interaction of endosomes and microtubules). The restin variants Restin-1, Restin-2, Restin-3, Restin-4, have been isolated from a human hemofiltrate peptide library
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