Rel homology domain |
RELM |
hemoglobin-alpha(110-125) |
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This Drosophila melanogaster gene (CG11992) encodes fly NF-kappa-B (Dushay et al, 1996), which is one of three NF-kappa-B family members found in Drosophila (the others being Dif [Dorsal-related immunity factor] and Dorsal).
Relish expression is induced strongly in infected flies and it therefore plays a role in immunity. Relish can activate the transcription of various antimicrobial peptides, including Cecropin A1, drosomycin, defensin
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